Version 2.77

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum Ab
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method

Additional Names

Short Name
H capsul Ab Titr Ser
Display Name
H. capsulatum Ab (S) [Titer]
Consumer Name Alpha Get Info
Histoplasma capsulatum antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.75
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) [anticuerpo anti - ] Histoplasma capsulatum [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) Histoplasma capsulatum Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Histoplasma capsulatum Ab:Título:Punto temporal:Suero:Cuantitativo:
fr-FR French (France) Histoplasma capsulatum Ac:Titre:Ponctuel:Sérum:Numérique:
fr-CA French (Canada) Histoplasma capsulatum , Ac:Titre:Temps ponctuel:Sérum:SemiQn:
it-IT Italian (Italy) Histoplasma capsulatum Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Titolo
ko-KR Korean (Korea, Republic Of) 히스토플라스마 캡슐라툼 항체:역가:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) Histoplasma capsulatum As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Histoplasma capsulatum Ac:Título:Pt:Soro:Qn:
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
zh-CN Chinese (China) 荚膜组织胞浆菌 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ab;自身抗体 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ab 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗体 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ab 美洲型组织胞浆菌抗体 荚膜组织胞浆菌 Ab 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌抗体

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=22347-9