24041-6
Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by Probe with signal amplification
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Part Description
LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cytomegalovirus DNA
- Property
- ACnc
- Time
- Pt
- System
- XXX
- Scale
- Qn
- Method
- Probe.amp.sig
Additional Names
- Short Name
- CMV DNA Spec Probe+sig amp-aCnc
- Display Name
- CMV DNA Probe+sig amp Qn (Specimen)
- Consumer Name Alpha Get Info
- Cytomegalovirus (CMV), Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0o
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19667
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Cytomegalie-Virus DNA: Synonyms: CMV |
| es-AR | Spanish (Argentina) | ADN de citomegalovirus: |
| es-ES | Spanish (Spain) | Citomegalovirus ADN: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | ADN de citomegalovirus: |
| fr-CA | French (Canada) | Cytomégalovirus , ADN: |
| fr-FR | French (France) | Cytomégalovirus ADN: |
| fr-BE | French (Belgium) | Cytomégalovirus ADN: Synonyms: CMV |
| it-IT | Italian (Italy) | Citomegalovirus DNA: Synonyms: Concentrazione Arbitraria Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del segnale Sonda di DNA |
| ko-KR | Korean (Korea, Republic Of) | 거대세포바이러스 디옥시리보핵산: |
| nl-NL | Dutch (Netherlands) | Cytomegalovirus DNA: |
| pt-BR | Portuguese (Brazil) | Citomegalovírus DNA: Synonyms: Deoxyribonucleic acid; |
| ru-RU | Russian (Russian Federation) | Цитомегаловирус ДНК: Synonyms: ДНК проба; |
| tr-TR | Turkish (Turkey) | Cytomegalovirus DNA: |
| zh-CN | Chinese (China) | 巨细胞病毒 DNA: Synonyms: CMV DNA CMV; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=24041-6
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright