40727-0
Hepatitis D virus Ab [Presence] in Serum by Immunoassay
Active
Part Descriptions
LP16711-1 Hepatitis D virus
Infection with the hepatitis delta virus (hepatitis delta-agent, HDV) is always seen in association with hepatitis B Virus (HBV) infection, where it may occur as a simultaneous acute infection or as an acute super-infection superimposed upon a case of chronic HBV hepatitis. This is an RNA virus that requires the presence of HBV for viral replication to occur. The serologic diagnosis of HDV depends upon the finding of HDV antigen and/or the presence of anti-HDV. Patients will almost invariably have detectable hepatitis B surface antigen (HBsAg) and/or antibodies to hepatitis core antigen (anti-HBc) and hepatitis Be antigen (HBeAg). In patients with acute co-infections, hepatitis D antigen (HDVAg) appears early after HBsAg does and disappears with convalescence. Acute HDV infections are associated with anti-HDV IgM antibody and chronic cases usually only demonstrate IgG antibody. Both antibodies may eventually disappear following convalescence. The simultaneous assessment of anti-HBc IgM will help to differentiate co-infections (present) from super-infections (absent). Information is from ARUP Laboratories.
Source: Regenstrief Institute
LP38345-2 Hepatitis D virus Ab
Hepatitis Delta Ab is detected in serum from patients who harbor the delta virus in the liver. It is a unique RNA virus that can cause either acute or chronic hepatitis. The virus is unique in that it requires HBV for replication -- therefore delta hepatitis develops only in HBS AG positive patients. The delta agent appears to circulate in the blood in low titer as a 35nm particle with a core of delta antigen and a surface component of HBsAG. The HBsAG encapsulates the delta agent and is, therefore, necessary for its replication. Infected individuals have delta viral particles in the liver and antibody to the virus. Infections with delta hepatitis may manifest itself in different cases: 1) as acute delta hepatitis concurrent with acute type B hepatitis; 2) as acute delta hepatitis occurring in a chronic HBsAG carrier; and 3) as chronic delta hepatitis occurring in a chronic HBsAG carrier. Acute delta hepatitis can be quite severe. Chronic delta hepatitis has been associated with cirrhosis and progressive chronic liver injury. Delta hepatitis should be suspected ONLY in patients who are HBsAG-positive. It is a common cause for acute hepatitis in the chronic HBsAG carrier especially if the patient is an intravenous drug abuser. The delta virus can cause a severe form of chronic hepatitis and should be suspected if there is sudden, unexplained deterioration or if acute liver disease is present in a HBsAG positive patient with HBsAG.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Hepatitis D virus Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- HDV Ab Ser Ql IA
- Display Name
- HDV Ab IA Ql (S)
- Consumer Name Alpha Get Info
- HDV antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4431
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Hepatitis-D-Virus Ak: Synonyms: Hepatitis delta virus |
| es-ES | Spanish (Spain) | Virus Hepatitis D Anticuerpos: |
| es-MX | Spanish (Mexico) | Virus de la hepatitis D Ab: |
| et-EE | Estonian (Estonia) | D-hepatiidi viirus antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Virus de l'hépatite D , Ac: |
| fr-FR | French (France) | Hépatite D virus Ac: |
| fr-BE | French (Belgium) | Virus de l'hépatite D Ac: Synonyms: Anticorps HVD |
| it-IT | Italian (Italy) | Epatite D, virus Ab: Synonyms: anticorpo Immunoassay Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus dell''epatite D |
| ko-KR | Korean (Korea, Republic Of) | D형 간염 바이러스 항체: |
| nl-NL | Dutch (Netherlands) | Hepatitis D-virus As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus zapalenia wątroby typu D Ab: Synonyms: Przeciwciała do wirusa zapalenia wątroby typu D |
| pt-BR | Portuguese (Brazil) | Hepatite D vírus Ac: Synonyms: HDVAc; |
| ru-RU | Russian (Russian Federation) | Гепатита D вирус Ат: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Hepatit D virüsü Ab: Synonyms: Ak İmmünölçüm, immünoassay Mevcut |
| uk-UA | Ukrainian (Ukraine) | Вірус гепатиту D Антитіла: Synonyms: ABS; |
| zh-CN | Chinese (China) | 丁型肝炎病毒 抗体: Synonyms: Ab; |
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