Version 2.77

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum DNA
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
H capsul DNA Spec Ql NAA+probe
Display Name
H. capsulatum DNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info
Histoplasma capsulatum, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
4716

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) ADN de Histoplasma capsulatum:concentración arbitraria:punto en el tiempo:XXX:ordinal:sonda.amplificación.blanco
es-ES Spanish (Spain) Histoplasma capsulatum ADN:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) ADN de Histoplasma capsulatum:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Histoplasma capsulatum , ADN:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
fr-FR French (France) Histoplasma capsulatum ADN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
fr-BE French (Belgium) Histoplasma capsulatum ADN:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
it-IT Italian (Italy) Histoplasma capsulatum DNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
ko-KR Korean (Korea, Republic Of) 히스토플라스마 캡슐라툼 디옥시리보핵산:임의농도:검사시점:XXX:순위척도:DNA 탐색자.증폭.표적
nl-NL Dutch (Netherlands) Histoplasma capsulatum DNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Histoplasma capsulatum DNA:ACnc:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Deoxyribonucleic acid; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
ru-RU Russian (Russian Federation) Histoplasma capsulatum ДНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Histoplazma Kapsulatum DNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf
Synonyms: Mevcut
zh-CN Chinese (China) 荚膜组织胞浆菌 DNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向
Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 皮疽组织胞浆菌 DNA 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 组织胞浆菌属 组织胞浆菌病 经过扩增的 美洲型组织胞浆菌 DNA 脱氧核糖核酸探针 鼻疽性组织浆菌 DNA

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5015-3