85380-4
HIV immunoassay testing algorithm interpretation in Serum, Plasma or Blood
Active
Term Description
This term is used to report the interpretation of results from an HIV immunoassay testing algorithm that may be based on third, fourth, fifth and possibly other generations of HIV immunoassays. HIV testing has evolved significantly in the past 30 years. The first three generations of HIV immunoassays detected HIV antibodies (first IgG only, then IgG and IgM). The fourth-generation tests can detect, but not differentiate between, HIV-1 and HIV-2 antibodies as well as the HIV-1 p24 antigen. The inclusion of the p24 antigen allows for detection of HIV as early as two weeks after exposure and before seroconversion occurs (i.e. before antibodies are produced). In 2014, the U.S. Centers for Disease Control and Prevention published a recommended algorithm for HIV diagnostic testing based on fourth-generation HIV immunoassays [https://stacks.cdc.gov/view/cdc23447]. More recently, fifth-generation HIV immunoassays have been developed, which can detect and differentiate between HIV-1 and HIV-2 antibodies and the HIV-1 p24 antigen. The CDC is in the process of updating its testing algorithm and the latest information can be found at https://www.cdc.gov/hiv/testing/laboratorytests.html. Note that third generation assays are still available in the U.S. and earlier generations may also be available outside the U.S.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- HIV immunoassay testing algorithm interpretation
- Property
- Imp
- Time
- Pt
- System
- Ser/Plas/Bld
- Scale
- Nom
- Method
Additional Names
- Short Name
- HIV IA algorithm interp SerPlBld-Imp
- Display Name
- HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]
- Consumer Name Alpha Get Info
- HIV immunoassay testing algorithm interpretation, Blood
Example Answer List: LL4332-4
Source: Association of Public Health Laboratories| Answer | Code | Score | Answer ID |
|---|---|---|---|
| No serologic evidence of infection with HIV. Cannot exclude incubating or early HIV infection. Submit second sample in 3-4 weeks if clinically indicated. | LA27091-0 | ||
| Serologic evidence of HIV-1 infection is present. Refer to physician for care. | LA27092-8 | ||
| Positive for HIV antibodies but could not be differentiated as HIV-1 or HIV-2. Refer to physician for care. | LA27115-7 | ||
| Serologic evidence of HIV-2 infection is present. Refer to physician for care. | LA27114-0 | ||
| Serologic evidence of acute HIV infection is present. Refer to physician for care and follow-up NAT testing. If NAT is nonreactive or not tested, submit second sample in 3-4 weeks to rule out HIV infection. | LA27116-5 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.61
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Interpretación del algoritmo de la prueba de inmunoensayo del HIV: |
| es-MX | Spanish (Mexico) | Interpretación del algoritmo de prueba de inmunoensayo del VIH: |
| fr-FR | French (France) | VIH interprétation test IA: |
| it-IT | Italian (Italy) | HIV, interpretazione algoritmo test dosaggio immunologico: Synonyms: Impressione/interpretazione di studio Interpretazione algoritmo test dosaggio immunologi Microbiologia Plasma Plasma o Sangue Punto nel tempo (episodio) Sangue Siero Siero o Plasma Siero,Plasma o Sangue |
| zh-CN | Chinese (China) | HIV 免疫测定法检测算法解释: Synonyms: AIDS; |
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