76544-6  Breast cancer 10-year risk of distant recurrence score Calculated by ProsignaBreast cancer 10-year risk of distant recurrence score Calculated by ProsignaBreast cancer 10Y risk of distant recurrence score: Score: Pt: ^Patient: Qn: Calculated.Prosigna  

NAME
  Fully-Specified Name: 
Component   Property   Time   System   Scale   Method
Breast cancer 10Y risk of distant recurrence score  Score  Pt  ^Patient  Qn  Calculated.Prosigna
  Long Common Name:  Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna
  Shortname:  Brst ca 10Y dist recur score Prosigna
  DisplayName:  Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna Score

TERM DEFINITION/DESCRIPTION(S)
  The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes: 1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years. This term was created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone.
 
 

BASIC ATTRIBUTES
  Class/Type: MOLPATH/Lab
  First Released in Version: 2.52
  Last Updated in Version: 2.63
  Order vs. Obs.: Both
  Status: Active.
Change Reason: Order_Obs: changed from 'observation' to 'both' to reflect that the LOINC code can also be used as an order code.

FORMULA -- READABLE
Calculated using a Cox model that includes coefficients for the gene expression assay results, proliferation score, and gross tumor size.

MEMBER OF THESE PANELS
  76546-1   Breast cancer 10-year risk of distant recurrence panel by ProsignaBreast cancer 10-year risk of distant recurrence panel by ProsignaBreast cancer 10Y risk of distant recurrence panel: -: Pt: ^Patient: -: Prosigna

PARTS

Part Type    Part No.  Part Name   
Component   LP188450-3  Breast cancer 10Y risk of distant recurrence score   [Breast cancer 10-year risk of distant recurrence score] 
Property   LP185820-0  Score 
Time   LP6960-1  Pt   [Point in time (spot)] 
Super System   LP6985-8  Patient 
Scale   LP7753-9  Qn 
Method   LP189620-0  Calculated.Prosigna   [Calculated by Prosigna] 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  乳腺癌远处转移 10 年风险评分:评分:时间点:^患者:定量型:计算法.Prosigna乳腺癌远处转移 10 年风险评分:评分:时间点:^患者:定量型:计算法.Prosigna
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  Cancer du sein score des risques de récidive sur 10 ans:Score:Ponctuel:Patient:Numérique:Test Prosigna calculCancer du sein score des risques de récidive sur 10 ans:Score:Ponctuel:Patient:Numérique:Test Prosigna calculCancer du sein score des risques de récidive sur 10 ans [Score] Patient ; Numérique ; Test Prosigna calcul
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Tumore della mammella, rischio 10 anni di recidive tumorali, punteggio:Punteggio:Pt:^Paziente:Qn:Calcolato.ProsignaTumore della mammella, rischio 10 anni di recidive tumorali, punteggio:Punteggio:Pt:^Paziente:Qn:Calcolato.Prosigna
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Ratio del riesgo de recurrencia a 10 años en el cáncer de mama:Puntuación:Punto temporal:^paciente:Qn:Calculado por ProsignaRatio del riesgo de recurrencia a 10 años en el cáncer de mama:Puntuación:Punto temporal:^paciente:Qn:Calculado por Prosigna

RELATED NAMES
  breast cancer PAM50 Random
  Brst ca 10Y risk dist recur score Point in time Risk of recurrence score
  Calc Prosigna ROR
  Calc.Prosigna QNT Scale
  Calculation Quan  
  Molecular pathology Quant  
  MOLPATH Quantitative  

EXAMPLE UNITS
  Unit  Source Type
  {score}  EXAMPLE UCUM UNITS 

UNITS (INTERNAL DETAILS)
  Source Type:  EXAMPLE UCUM UNITS 
  Unit:  {score} 

CHANGE HISTORY
  Change Type: MIN

INTERNAL FIELDS
  Detail Page Created On: 9/26/2018 7:50:28 PM
  Long Common Name: Breast cancer 10-year risk of distant recurrence score Calculated by Prosigna
  Shortname: Brst ca 10Y dist recur score Prosigna
  Fully Specified Name: Breast cancer 10Y risk of distant recurrence score: Score: Pt: ^Patient: Qn: Calculated.Prosigna
     
  Component Word Count: 8
  ID: 78801
  Status (Raw): ACTIVE