85300-2  Mitotic rate [Score] in Breast cancer specimen Qualitative by NottinghamMitotic rate [Score] in Breast cancer specimen Qualitative by NottinghamMitotic rate: Score: Pt: Breast cancer specimen: Ord: Nottingham  

NAME
  Fully-Specified Name: 
Component   Property   Time   System   Scale   Method
Mitotic rate  Score  Pt  Breast cancer specimen  Ord  Nottingham
  Long Common Name:  Mitotic rate [Score] in Breast cancer specimen Qualitative by Nottingham
  Shortname:  Mitotic rate Br ca spec Ql Nottingham
  DisplayName:  Mitotic rate Nottingham Ql (Breast cancer specimen)

PART DEFINITION/DESCRIPTION(S)
  Part: Mitotic rate
  The degree of mitotic activity in breast carcinoma is one component of the Nottingham histologic grade (NHG) [LOINC: 44648-4] , which is a prognostic indicator for patients with breast carcinoma. The two other components of the NHG are tubule formation [LOINC: 85321-8] and nuclear pleomorphism [LOINC: 44645-0] . Mitotic activity is assessed as the number of mitoses per 10 high power fields (HPF), with increasing mitotic activity being an indicator of more aggressive cancer. The specific scores assigned to the number of mitoses depends on the size of the HPF. For example, for a HPF size of 0.274 mm^2, less than 10 mitoses per 10 HPF gets a score of 1, 10-19 gets a score of 2, and greater than or equal to 20 gets a score of 3. When larger or smaller HPFs are used, the cutoffs for the number of mitoses corresponding to a specific score are adjusted according to published guidelines. [PMID: 11865000]
 
 

BASIC ATTRIBUTES
  Class/Type: PATH/Lab
  First Released in Version: 2.61
  Last Updated in Version: 2.61
  Order vs. Obs.: Observation
  Status: Active

NORMATIVE ANSWER LIST    (LL4383-7)  
 
Source: College of American Pathologists
  SEQ#        Answer        Score        Answer ID    
  1       Score 1       1       LA27225-4  
  2       Score 2       2       LA27226-2  
  3       Score 3       3       LA27227-0  
  4       No residual invasive carcinoma after presurgical (neoadjuvant) therapy       0       LA27220-5  
  5       Score cannot be determined       0       LA27221-3  

MEMBER OF THESE PANELS
  85904-1   Cancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel: -: Pt: Breast cancer specimen: -: CAP cancer protocols

PARTS

Part Type    Part No.  Part Name   
Component   LP247956-8  Mitotic rate 
Property   LP185820-0  Score 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP247851-1  Breast cancer specimen 
Scale   LP7751-3  Ord 
Method   LP248063-2  Nottingham 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  有丝分裂率:评分:时间点:乳腺癌标本:序数型:诺丁汉法有丝分裂率:评分:时间点:乳腺癌标本:序数型:诺丁汉法
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Tasso mitotico:Punteggio:Pt:Tumore della mammella, campione:Ord:NottinghamTasso mitotico:Punteggio:Pt:Tumore della mammella, campione:Ord:Nottingham
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  indice mitotico:Puntuación:Punto temporal:Muestra de cancer de mama:Ord:Nottinghamindice mitotico:Puntuación:Punto temporal:Muestra de cancer de mama:Ord:Nottingham

RELATED NAMES
  Br ca spec Pathology Random
  Brst Point in time Scale
  CA QL Screen
  Ca spec Qual Spec
  Ordinal Qualitative  

CHANGE HISTORY
  Change Type: ADD

INTERNAL FIELDS
  Detail Page Created On: 9/26/2018 5:42:32 PM
  Long Common Name: Mitotic rate [Score] in Breast cancer specimen Qualitative by Nottingham
  Shortname: Mitotic rate Br ca spec Ql Nottingham
  Fully Specified Name: Mitotic rate: Score: Pt: Breast cancer specimen: Ord: Nottingham
     
  Component Word Count: 2
  ID: 90727
  Status (Raw): ACTIVE