85318-4  HER2 [Presence] in Breast cancer specimen by FISHHER2 [Presence] in Breast cancer specimen by FISHHER2: PrThr: Pt: Breast cancer specimen: Ord: FISH  

NAME
  Fully-Specified Name: 
Component   Property   Time   System   Scale   Method
HER2  PrThr  Pt  Breast cancer specimen  Ord  FISH
  Long Common Name:  HER2 [Presence] in Breast cancer specimen by FISH
  Shortname:  Her2 Br ca spec Ql FISH
  DisplayName:  HER2 FISH Ql (Breast cancer specimen)

PART DEFINITION/DESCRIPTION(S)
  Part: HER2
  HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340 (cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.
  Copyright: Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
 
 
  Part: FISH
  FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues.
  Copyright: Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
 
 

BASIC ATTRIBUTES
  Class/Type: MOLPATH/Lab
  First Released in Version: 2.61
  Last Updated in Version: 2.61
  Order vs. Obs.: Observation
  Status: Active

EXAMPLE ANSWER LIST    (LL2009-0)  
 
Source: ARUP Laboratories
  SEQ#        Answer        Answer ID    
  1       Positive
http://snomed.info/sct ©: 10828004 Positive (qualifier value)    
  LA6576-8  
  2       Negative
http://snomed.info/sct ©: 260385009 Negative (qualifier value)    
  LA6577-6  
  3       Equivocal
http://snomed.info/sct ©: 42425007 Equivocal (qualifier value)    
  LA11885-3  

MEMBER OF THESE PANELS
  85904-1   Cancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel: -: Pt: Breast cancer specimen: -: CAP cancer protocols

PARTS

Part Type    Part No.  Part Name   
Component   LP28442-9  HER2 
Property   LP217195-9  PrThr   [Presence or Threshold] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP247851-1  Breast cancer specimen 
Scale   LP7751-3  Ord 
Method   LP62864-1  FISH   [Fluorescent in situ hybridization (FISH)] 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  Her2:存在情况或阈值:时间点:乳腺癌标本:序数型:FISHHer2:存在情况或阈值:时间点:乳腺癌标本:序数型:FISH
  French (FRANCE)  (From: ASIP Santé (Agence des systèmes d'information partagés de santé))
 
  HER2:Présence/​Seuil:Ponctuel:Tissu mammaire cancereux:Qualitatif:FISHHER2:Présence/​Seuil:Ponctuel:Tissu mammaire cancereux:Qualitatif:FISHHER2 [Présence/​Seuil] Tissu mammaire cancereux ; Qualitatif ; FISH
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  HER2:PrThr:Pt:Tumore della mammella, campione:Ord:FISHHER2:PrThr:Pt:Tumore della mammella, campione:Ord:FISH
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Factor de crecimiento epidérmico humano tipo 2:PrThr:Punto temporal:Muestra de cancer de mama:Ord:Hibridación in situ fluoresente (FISH)Factor de crecimiento epidérmico humano tipo 2:PrThr:Punto temporal:Muestra de cancer de mama:Ord:Hibridación in situ fluoresente (FISH)

RELATED NAMES
  Br ca spec erbB2 PR
  Brst Fluorescent in situ hybridization QL
  CA HER-2 Qual
  Ca spec HER-2/neu Qualitative
  C-ERBB-2 Molecular pathology Random
  erb MOLPATH Screen
  ERB2 Ordinal Spec
  ERB-2 Point in time  

CHANGE HISTORY
  Change Type: ADD

INTERNAL FIELDS
  Detail Page Created On: 9/26/2018 5:42:26 PM
  Long Common Name: HER2 [Presence] in Breast cancer specimen by FISH
  Shortname: Her2 Br ca spec Ql FISH
  Fully Specified Name: HER2: PrThr: Pt: Breast cancer specimen: Ord: FISH
     
  Component Word Count: 1
  ID: 90745
  Status (Raw): ACTIVE

3rd PARTY COPYRIGHT
  Code System: http://snomed.info/sct
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