85321-8  Glandular differentiation [Score] in Breast cancer specimen Qualitative by NottinghamGlandular differentiation [Score] in Breast cancer specimen Qualitative by NottinghamGlandular differentiation: Score: Pt: Breast cancer specimen: Ord: Nottingham  

NAME
  Fully-Specified Name: 
Component   Property   Time   System   Scale   Method
Glandular differentiation  Score  Pt  Breast cancer specimen  Ord  Nottingham
  Long Common Name:  Glandular differentiation [Score] in Breast cancer specimen Qualitative by Nottingham
  Shortname:  Gland diff Br ca spec Ql Nottingham
  DisplayName:  Glandular differentiation Nottingham Ql (Breast cancer specimen)

PART DEFINITION/DESCRIPTION(S)
  Part: Glandular differentiation
  The degree of glandular differentiation or tubule formation in breast carcinoma is one component of the Nottingham histologic grade (NHG) [LOINC: 44648-4] , which is a prognostic indicator for patients with breast carcinoma. The two other components of the NHG are nuclear pleomorphism [LOINC: 44645-0] and mitotic activity [LOINC: 85300-2] . Less aggressive cancers have more tubule formation, with scores assigned as follows:
1 = greater than 75% of the tumor area contains tubular or glandular structures
2 = 10 to 75% of the tumor area contains tubular structures
3 = less than 10% of the tumor area contains tubular structures
[PMID: 11865000]
 
 

BASIC ATTRIBUTES
  Class/Type: PATH/Lab
  First Released in Version: 2.61
  Last Updated in Version: 2.61
  Order vs. Obs.: Observation
  Status: Active

NORMATIVE ANSWER LIST    (LL4380-3)  
 
Source: College of American Pathologists
  SEQ#        Answer        Score        Answer ID    
  1       Score 1: >75% of tumor area forming glandular/tubular structures       1       LA27216-3  
  2       Score 2: 10% to 75% of tumor area forming glandular/tubular structures       2       LA27217-1  
  3       Score 3: <10% of tumor area forming glandular/tubular structures       3       LA27218-9  
  4       Only microinvasion present (not graded)       0       LA27219-7  
  5       No residual invasive carcinoma after presurgical (neoadjuvant) therapy       0       LA27220-5  
  6       Score cannot be determined       0       LA27221-3  

MEMBER OF THESE PANELS
  85904-1   Cancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel - Breast cancer specimen by CAP cancer protocolsCancer pathology panel: -: Pt: Breast cancer specimen: -: CAP cancer protocols

PARTS

Part Type    Part No.  Part Name   
Component   LP247955-0  Glandular differentiation 
Property   LP185820-0  Score 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP247851-1  Breast cancer specimen 
Scale   LP7751-3  Ord 
Method   LP248063-2  Nottingham 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  腺体分化:评分:时间点:乳腺癌标本:序数型:诺丁汉法腺体分化:评分:时间点:乳腺癌标本:序数型:诺丁汉法
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Differenziazione ghiandolare:Punteggio:Pt:Tumore della mammella, campione:Ord:NottinghamDifferenziazione ghiandolare:Punteggio:Pt:Tumore della mammella, campione:Ord:Nottingham
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  difeencacion glandular:Puntuación:Punto temporal:Muestra de cancer de mama:Ord:Nottinghamdifeencacion glandular:Puntuación:Punto temporal:Muestra de cancer de mama:Ord:Nottingham

RELATED NAMES
  Br ca spec Pathology Scale
  Brst Point in time Screen
  CA QL Spec
  Ca spec Qual  
  Gland diff Qualitative  
  Ordinal Random  

CHANGE HISTORY
  Change Type: ADD

INTERNAL FIELDS
  Detail Page Created On: 9/26/2018 5:42:25 PM
  Long Common Name: Glandular differentiation [Score] in Breast cancer specimen Qualitative by Nottingham
  Shortname: Gland diff Br ca spec Ql Nottingham
  Fully Specified Name: Glandular differentiation: Score: Pt: Breast cancer specimen: Ord: Nottingham
     
  Component Word Count: 2
  ID: 90748
  Status (Raw): ACTIVE