91545-4  Myelin oligodendrocyte glycoprotein Ab [Presence] in Serum by Cell binding assay immunofluorescent assayMyelin oligodendrocyte glycoprotein Ab [Presence] in Serum by Cell binding assay immunofluorescent assayMyelin oligodendrocyte glycoprotein Ab: PrThr: Pt: Ser: Ord: CBA IFA  

NAME
  Fully Specified Name: 
Component   Property   Time   System   Scale   Method
Myelin oligodendrocyte glycoprotein Ab  PrThr  Pt  Ser  Ord  CBA IFA
  Long Common Name:  Myelin oligodendrocyte glycoprotein Ab [Presence] in Serum by Cell binding assay immunofluorescent assay
  Short Name:  MOG Ab Ser Ql CBA IFA
  Display Name:  Myelin oligodendrocyte glycoprotein Ab Cell binding assay immunofluorescent assay Ql (S)

PART DEFINITION/DESCRIPTION(S)
  Part: Myelin oligodendrocyte glycoprotein Ab
  Myelin oligodendrocyte glycoprotein (MOG) is a protein made up of two polypeptides with molecular masses of 26 and 28 kilodaltons, respectively. MOG is located on the surface of myelin and oligodendrocyte cytoplasmic membranes and binds to the monoclonal antibody 8-18C5. [PMID: 1373175] MOG is a probable autoantigen target associated with multiple sclerosis (MS) and other demyelinating diseases (DD) of the central nervous system. [PMID: 1373175] That being said, there is variation in the level of MOG antibody found in patients with MS and DD with inconsistencies between MOG antibody measurements using western blot and ELISA test methods, making it a questionable biomarker for DD. [PMID: 17294606] MOG IgG1 is the most prevalent isotype of IgG in patients with DD. [PMID: 29063242]
 
 

BASIC ATTRIBUTES
  Class/Type: SERO/Lab
  First Released in Version: 2.66
  Last Updated in Version: 2.66
  Order vs. Obs.: Both
  Status: Active

NORMATIVE ANSWER LIST    (LL360-9)  
 
Source: Regenstrief Institute
  SEQ#        Answer        Answer ID    
  1       Positive
http://snomed.info/sct ©: 10828004 Positive (qualifier value)    
  LA6576-8  
  2       Negative
http://snomed.info/sct ©: 260385009 Negative (qualifier value)    
  LA6577-6  

PARTS

Part Type    Part No.  Part Name   
Component   LP231891-5  Myelin oligodendrocyte glycoprotein Ab 
Component   LP231890-7  Myelin oligodendrocyte glycoprotein 
     Suffix   LP20667-9  Ab 
Property   LP217195-9  PrThr   [Presence or Threshold] 
Time   LP6960-1  Pt   [Point in time (spot)] 
System   LP7567-3  Ser   [Serum] 
Scale   LP7751-3  Ord 
Method   LP269367-1  CBA IFA   [Cell binding assay immunofluorescent assay] 
Fragments for synonyms   LP21219-8  Glycoprotein 

LANGUAGE VARIANTS
  Chinese (CHINA)  (From: Regenstrief-generated full translation based on part translation provided by Lin Zhang, A LOINC volunteer from China)
 
  髓鞘少突胶质细胞糖蛋白 抗体:存在情况或阈值:时间点:血清:序数型:CBA IFA髓鞘少突胶质细胞糖蛋白 抗体:存在情况或阈值:时间点:血清:序数型:CBA IFA
  Italian (ITALY)  (From: Regenstrief-generated full translation based on part translation provided by Consiglio Nazionale delle Ricerche)
 
  Glicoproteina oligodendrocita mielinica , Ab:PrThr:Pt:Siero:Ord:CBA IFAGlicoproteina oligodendrocita mielinica , Ab:PrThr:Pt:Siero:Ord:CBA IFA
  Spanish (SPAIN)  (From: Regenstrief-generated full translation based on part translation provided by the Clinical Laboratory Committee of SERVICIO EXTREMEÑO DE SALUD, with the support of BITAC MAP.)
 
  Mielina de oligodendrocitos glicoproteína Anticuerpos:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)Mielina de oligodendrocitos glicoproteína Anticuerpos:PrThr:Punto temporal:Suero:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)

RELATED NAMES
  ABS Glycoprot QL
  Aby Glycoproteins Qual
  Antby GP Qualitative
  Anti Indirect Fluorescence Antibody Random
  Antibodies MOG Screen
  Antibody MOG Ab Serology
  Autoantibodies Ordinal Serum
  Autoantibody Point in time SR
  gG PR  

CHANGE HISTORY
  Change Type: ADD

INTERNAL FIELDS
  Detail Page Created On: 6/26/2019 12:00:23 PM
  Long Common Name: Myelin oligodendrocyte glycoprotein Ab [Presence] in Serum by Cell binding assay immunofluorescent assay
  Shortname: MOG Ab Ser Ql CBA IFA
  Fully Specified Name: Myelin oligodendrocyte glycoprotein Ab: PrThr: Pt: Ser: Ord: CBA IFA
     
  Component Word Count: 4
  ID: 98929
  Status (Raw): ACTIVE

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  Code System: http://snomed.info/sct
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